Research Scientist II, Molecular Biology RNA
Company: Takeda Pharmaceutical
Location: National City
Posted on: May 12, 2022
Job Description:
By clicking the "Apply" button, I understand that my employment
application process with Takeda will commence and that the
information I provide in my application will be processed in line
with Takeda's and . I further attest that all information I submit
in my employment application is true to the best of my
knowledge.Job DescriptionOBJECTIVES/PURPOSE We are seeking a highly
motivated Research Scientist II with in-depth experience in
Molecular Biology to join Drug Discovery Sciences (DDS) department
at Takeda San Diego. This individual will perform various molecular
biology assays including DNA/RNA manipulations and mammalian cell
culture and support drug discovery projects. The successful
applicant should have extensive bench research experience and enjoy
a laboratory-focused role in a fast-paced, multidisciplinary team
setting.ACCOUNTABILITIES - - - - - - - - - - - - -
- Manipulation of DNA (genomic DNA isolation/manipulation,
recombinant plasmid generation/manipulation, lentivirus &
adenovirus generation/transduction, gene editing by CRISPR, library
prep for NGS)
- Manipulation of RNA (RNA isolation/manipulation, cDNA
synthesis, design and transfection of siRNA/ASO, in vitro
transcription, sample prep for NGS)
- Characterize protein expression and function using various
molecular/cell biology and biochemical methods
- Generate, analyze and interpret data in appropriate scientific
context, and present data in group meetings, project team meetings,
and department meetings
- Regularly document experimental results in electronic
notebooksTechnical/Functional (Line) Expertise
- Demonstrates well-developed knowledge of related areas such as
protein chemistry, cell biology and biophysics
- Strong understanding of the drug discovery processLeadership
- Designs and directs research strategy and activities to meet
program objectives; provide leadership, timelines and contingency
plans - - - - - - - - - - - -Decision-making and Autonomy
- Independently manages workload and expectations
- Scientifically independent
- Scientific driver for research strategy that impacts group
internally and outside area of function -Interaction
- Initiates and leads external interactions and
collaborations
- Frequent contact with internal and external personnel at
various management levels
- Collaborates with other departments, and disciplines, acting as
scientific authority within discipline
- Serves as senior company / project representative at external
conferences, or business meetingsEDUCATION, BEHAVIOURAL
COMPETENCIES AND SKILLS: -
- Ph.D. in Cell/Molecular Biology, Biochemistry or related field
with 1-3 years, MS with 4-6+, or BS with 6-8+ years of drug
discovery experience in industry setting.
- Extensive experience with cloning, mammalian cell culture,
transfection/transduction, siRNA/ASO design and transfection,
western blot/HTRF/ELISA is required.
- Experience with high throughput assays with compound testing is
strongly preferred.
- Knowledge on RNA splicing and protein translation is strongly
desired.
- Must demonstrate the ability to design, execute experiments and
troubleshoot independently.
- Strong communication skills and ability to work collaboratively
in a fast-paced, multidisciplinary team setting are required.In
accordance with the CO Equal Pay Act, -Colorado Applicants Are Not
Permitted to Apply.EEO StatementTakeda is proud in its commitment
to creating a diverse workforce and providing equal employment
opportunities to all employees and applicants for employment
without regard to race, color, religion, sex, sexual orientation,
gender identity, gender expression, parental status, national
origin, age, disability, citizenship status, genetic information or
characteristics, marital status, status as a Vietnam era veteran,
special disabled veteran, or other protected veteran in accordance
with applicable federal, state and local laws, and any other
characteristic protected by law.LocationsSan Diego, CAWorker
TypeEmployeeWorker Sub-TypeRegularTime TypeFull time
Keywords: Takeda Pharmaceutical, National City , Research Scientist II, Molecular Biology RNA, Other , National City, California
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