Bioinformatics Scientist II
Company: Exact Sciences
Location: San Diego
Posted on: April 19, 2024
Job Description:
Help us change lives
At Exact Sciences, we're helping change how the world prevents,
detects and guides treatment for cancer. We give patients and
clinicians the clarity needed to make confident decisions when they
matter most. Join our team to find a purpose-driven career, an
inclusive culture, and robust benefits to support your life while
you're working to help others.
Position Overview
The Bioinformatics Scientist II, with limited guidance from more
experienced scientists, works individually and in collaboration
with wet lab scientists on multiple projects which are moderate to
complex in scope. The Bioinformatics Scientist II plays an active
role or leads in the planning of projects and analyses and is often
the bioinformatics lead responsible for the successful execution of
the project. This position involves independently making detailed
observations, analyzing data, interpreting results, and providing
insights into the next steps of the project.
Working in a team setting, the Bioinformatics Scientist II will be
involved in Research projects serving as a bioinformatics lead or a
subject matter expert in in evaluating research ideas and concepts
in their feasibility towards development of diagnostic assay
products. Experience in methylation and RNA Seq preferred.
Essential Duties
Include, but are not limited to, the following:
- Conduct analyses within several product or technology areas and
identify problems and discrepancies.
- Independently plan and analyze results of bench level
experiments within several product or technology areas.
- Analyze research/experimental data, interpret the results, and
provide insights into the next steps.
- Manage bench-generated data and bioinformatics outputs within
high performance computing (HPC) or cloud computing
environment.
- Utilize and apply methods or technologies effectively and
provide ideas for new techniques, when appropriate.
- Maintain knowledge of technological industry developments that
could assist in completion of an assignment or aid in the
development of new processes or procedures.
- Provide technical input and participate in decisions affecting
project planning and experimental design.
- Prepare and provide information and data for scientific
abstracts/conferences/project meetings/publication.
- Generate, document, and communicate development plans for
critical aspects of a project.
- Develop research plans and experimental outlines to write
experimental protocols and perform laboratory experiments.
- Prepare detailed technical procedures, protocols, and
reports.
- Evaluate impact of nonconforming data to product or
process.
- Identify and address trends in study data.
- Prepare and approve written reports.
- Lead identification of areas for process improvements.
- Maintain lab notebook in a clear, complete, and consistent
manner, following all legal, ISO, and QSR requirements.
- Prepare reports and documentation providing the analysis or
summarization of results, outcomes and next steps to supervisor,
technical teams/groups, or project teams.
- Present experimental results and defend scientific ideas and
findings at data meetings, group meetings, project team meetings,
and/or departmental meetings, lead meetings as subject matter
expert.
- Demonstrate technical proficiency and knowledge, scientific
creativity, collaboration with others, and independent thought and
ability to provide insights and defend scientific ideas.
- Work on problems of diverse and complex in scope in which
analysis of data requires in-depth evaluation of identifiable
factors.
- Exercise judgment within broadly defined practices and policies
in selecting methods, techniques, and evaluation criteria for
obtaining solutions.
- Work on individual assignments and with project team members as
appropriate to meet department and project objectives.
- Work within project timeframes with successful outcomes on
multiple projects and key responsibilities.
- Act as bioinformatics leader for one or more projects that are
moderate to complex in scope.
- Act as subject matter expert in core team and/or
cross-functional meetings.
- Exercise discretion and independent judgement within broadly
defined practices and policies in: selecting methods, techniques
and evaluation criteria for obtaining and interpreting results;
analyzing data and presenting findings in a professional and
knowledgeable manner.
- Promote an open, collaborative environment built on trust to
foster positive teamwork.
- Assist in planning and recommendation of activities that
account for prioritization of organizational and department
goals.
- Ability to train and mentor research associates.
- Ability to organize, present, and convey moderate problems or
issues.
- Communicate clearly and frequently with all levels of the
organization; including team members, project team members (core
and extended), functional managers, clinical lab, and other
stakeholders.
- Create high quality presentations that effectively communicate
and tie into a cohesive story the project status and/or
experimental results.
- Apply strength in performing complex analyses and the ability
to present data and recommendations to a variety of audiences
throughout an organization.
- Apply qualitative and analytical skills with strong attention
to detail.
- Ability to effectively work on several varied projects at one
time, with frequent changing priorities.
- Demonstrate excellent analytical, problem solving and
decision-making skills.
- Apply sound technical knowledge and ability gained through
experience and/or learning.
- Apply previous knowledge and outcomes to new and valuable
problems (able to make predictions based on a deep understanding of
the fundamental nature of the inputs into a decision or
action).
- Uphold company mission and values through accountability,
innovation, integrity, quality, and teamwork.
- Support and comply with the company's Quality Management System
policies and procedures.
- Maintain regular and reliable attendance.
- Ability to act with an inclusion mindset and model these
behaviors for the organization.
- Ability to work on a mobile device, tablet, or in front of a
computer screen and/or perform typing for approximately 90% of a
typical working day.
- Ability to work on a computer and phone simultaneously.
- Ability to travel 5% of working time away from work location,
may include overnight/weekend travel. Minimum Qualifications
- PhD in bioinformatics, computational biology, computer science,
mathematics, or related field; or Master's degree in
bioinformatics, computational biology, computer science,
mathematics, or related field plus 4 years of experience in lieu of
a PhD; or Bachelor's degree in bioinformatics, computational
biology, computer science, mathematics, or related field plus 6
years of experience in lieu of PhD.
- 3+ years of industry or academia experience in
bioinformatics.
- 2+ years of experience in medical device/IVD, biotech, life
science or pharmaceutical industry.
- Extensive experience in Linux-based HPC or cloud computing
environments and associated tools.
- Ability to write custom code in at least three programming or
scripting languages
- Proficient in the principles of molecular biology and/or
biochemistry and/or next-generation sequencing (NGS) and
genomics
- Familiarity with product/assay research, design, or
development
- Working knowledge of statistical and mathematical methods in
biology/genetics, including experience with statistical software,
such as JMP or R.
- Basic computer skills to include Internet navigation, Email
usage, and word processing.
- Proficient in Microsoft Office to include Excel, Word, and
PowerPoint.
- Demonstrated ability to perform the essential duties of the
position with or without accommodation.
- Authorization to work in the United States without sponsorship.
Preferred Qualifications
- 5+ years of experience in medical device/IVD, biotech, life
science or pharmaceutical industry.
- Previous industry experience in product development or
technical support.
- Background containing a substantial amount of bioinformatics
work including troubleshooting.
- Previous experience working in a molecular diagnostics/clinical
laboratory setting.
- Demonstrable ability to apply statistical approaches to analyze
data, interpret and present results Excellent analytical and
programming skills (strong experience in shell scripting, R and
Python)
- Ability to produce reproducible code (R Markdown, Jupyter
notebooks, etc.)
- Excellent communication and presentation skills, ability to
work across functional teams and with non-experts.
- Experience in selecting and benchmarking methods and tools and
designing new quality metrics and processes for NGS-based
assays.
- Ability to apply and develop innovative analysis approaches
when standard methods are inadequate.
- Fluency in contemporary data visualization methods.
Salary Range:
$119,000.00 - $190,000.00
The annual base salary shown is for this position located in US -
CA - San Diego on a full-time basis. In addition, this position is
bonus eligible, and is eligible to receive company stock upon hire
as well as annually.
Exact Sciences is proud to offer an employee experience that
includes paid time off (including days for vacation, holidays,
volunteering, and personal time) . click apply for full job
details
Keywords: Exact Sciences, National City , Bioinformatics Scientist II, Other , San Diego, California
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